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The Cutting Edge Science of
the Human Microbiome, Put into Action

At Olawell our founders and scientific advisors have taken decades of advanced research and science of the human microbiome and turned it into an actionable and easy to understand test for food intolerance. ​​​​​​​

We Are Engaged in Bringing You
the Best Solution for Your Gut

What exactly is my microbiome and what does it do? Your microbiome – the collection of millions of bacteria in and on your body, is a complex ecosystem involved in many different metabolic, immune, and energy conversion processes (1). Your gut microbiome has the potential to increase the extraction of energy and nutrients from the food you eat, as well as provide enzymes and vitamins for the cells lining your gut. It also contributes to the development of your immune system (2).

What is food intolerance?

Food intolerance is described as a difficulty digesting certain foods. Many people experience unpleasant digestive conditions, such as stomach pain, bloating, diarrhea, skin rashes, and itching. Food allergies and food intolerance are not the same. Food intolerance does not involve your immune system – there is no allergic reaction. It is not life-threatening and symptoms occur hours after eating a considerable amount of a specific food. With a food allergy, just a trace amount of a certain food can cause a potentially fatal reaction. Many research studies suggest that alterations in the normal gut microbiome composition impact the development of food intolerances. At the same time, the right balance of the gut microbiota may decrease susceptibility to food intolerance and improve gut health.

Why is it important to have a balanced & healthy microbiome? There is a growing body of evidence that reveals links between the gut microbiome and overall health. For example, a number of studies in humans and animals have shown a correlation between the gut microbiome and different diseases. These include metabolic, respiratory, autoimmune, psychological, and liver diseases, as well as gastrointestinal cancers and various infections (3).

What is an example of a good diet/microbiome?

Research indicates that there are two populations – the Japanese and Mediterranean, whose health and longevity may be used as a model for other populations. The Japanese population has a disproportionate share of the world’s centenarians (people who live 100+ years) and supercentenarians (people who live 110+ years) (4). They also have an extremely low risk of heart disease, most cancers, Alzheimer’s disease, and obesity. While multiple factors contribute to Japan’s #1 longevity status, their diet is considered a key driver of their success (5). Traditional Mediterranean diets are also considered among the healthiest (6). The healthiest and longest-lived among Mediterranean people are concentrated in a band that runs from northwestern Italy, across southern France, and into Spain. Randomized controlled trials show that these diets provide substantial health benefits over other common diets. And two such trials (the Lyon Heart Health Study, and PREDIMED) show that emphasizing Mediterranean components relative to a standard modern Mediterranean diet has substantial health benefits.

How do you create my personal food recommendations?

Longevity depends on many factors, and while a specific gut microbiome composition alone will not guarantee a long and healthy life, it is most likely a key contributor. OlaWell has established profiles from these ideal diets to use as standards of comparison against customers' initial microbiome profiles. From this baseline, subsequent dietary recommendations are made, designed to shift the customer microbiome profile closer to the ideal. Our platform has been enabled with machine learning algorithms, which allows us to improve our recommendation engine further. Having access to a large set of individual microbiome data greatly helps us improve our system for end-users. With this in mind, we have established a collaboration with Harvard’s Personal Genome Project. This will benefit our reporting capabilities as well as help us further fine-tune all aspects of our service.

See our blog for more
The Microbiome Read more
Individualized Responses of Gut Microbiome to Diet and Their Role in Gastrointestinal Psychology Read more
Diet rapidly and reproducibly alters the human gut microbiome Read more
Richness of human gut microbiome correlates with metabolic markers Read more
Host-gut microbiota metabolic interactions Read more
Linking long-term dietary patterns with gut microbial enterotypes Read more
Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa Read more
Dominant and diet-responsive groups of bacteria within the human colonic microbiota Read more
The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice Read more
A core gut microbiome in obese and lean twins Read more
Human gut microbes associated with obesity Read more
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